Posts Tagged ‘nucleus accumbens’

Opioid receptors

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A sub-population of the striatal direct-pathway neurons, known for being connected to voluntary movement, can be the basis of opiate-reward driven activities. The brain’s opioid system is basic to the reward value of stimuli and consequent behaviours. Opioid receptors bind to the brain’s opioid peptides such as enkephalin, β-endorphin, or dynorphin. μ-opioid receptors act to suppress the neuronal activity of neurons that otherwise…

Emotional valence

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Visualising an emotional valence map in the limbic forebrain Jianbo Xiu et al, Chinese Academy of Sciences Nature Neuroscience, Vol. 17, No. 11, November 2014 www.nature.com/neuro Summary and review of the above paper The representation of emotional valences in the brain has long been regarded as a fundamental problem. Emotions are categorised along two dimensions, firstly valence or value ranging from negative to positive, and secondly, salience or intensity ranging from weak to strong. This Read more […]

Learning in the nucleus accumbens

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Learning and memory: Teaching the accumbens a valuable lesson Nature Reviews Neuroscience 14, 2-3, January 2013, doi.1038/nrn3419 Dopamine is the neurotransmitter most involved in learning from environmental stimuli. This involves projections from neurons in the ventral tegmental (VTA) to the nucleus accumbens in the basal ganglia. This paper discusses an additional influence involving projections of the inhibitory neurotransmitter GABA. These also project from the ventral tegmental to the Read more […]

Dopamine and motivation

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The influence of dopamine in generating action from motivation Mark Walton, Jerylin Gan & Paul Phillips In:-  Neural Basis of Motivational and Cognitive Control  –  MIT Press (2011) Keywords:  dopamine, midbrain, basal ganglia, nucleus accumbens, opioid neurotransmitters The release of dopamine into the striatum and particularly the nucleus accumbens is closely related to the subjective evaluation of sensory inputs, and to the subsequent selection of behaviour and actions. The Read more […]

Dopamine & Decisions

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Dopamine and conscious decision making Anthony Grace In:- New Horizons in the Neuroscience of Consciousness INTRODUCTION:  This chapter discusses the interaction of the prefrontal cortex, the ventral subiculum in the hippocampal region and the dopamine system. These interact in particular in the nucleus accumbens area of the basal ganglia. This is important with respect to their role in decision making and behavioural responses. Dopamine also helps to establish long-term potentiation (LTP) Read more […]