Posts Tagged ‘consciousness’

Anaesthetics & consciousness 2

Posted by

Halothane binding proteome in human brain cortex  ::  Roderic Eckenhoff, Maryellen Eckenhoff et al, University of Pennsylvania  ::  Journal of Proteome Research, 2007, 6, pp. 582-592  ::  http://pubs.acs.org/doi/pdf/10.1021/pr060311u Summary and review of the above paper This later study demonstrated that anaesthetics could interact with many human brain proteins; previous studies has been confined to rodent brains. Recent research has expanded rather than contracted the potential targets Read more […]

Anaesthetics and mitochondria

Posted by

Inhalational anaesthetic-binding proteins in neuronal membrane Jin Xi, Maryellen Eckenhoff, Roderic Eckenhoff et al, University of Pennsylvania & Amersham Biosciences  ::  The Journal of Biological Chemistry, Vol. 279, No. 19, May 7 2004, pp. 19628-19633  :: http://www.jbc.org/content/279/19/19628.full.pdf+html Summary and review of the above paper In this study 34 binding sites were identified for the anaesthetic halothane. Within this group, mitochondrial proteins especially those Read more […]

Anaesthetics and consciousness

Posted by

Anaesthetics act in quantum channels in brain microtubules to prevent consciousness Travis Craddock, Stuart Hammerof, Jack Tuszynski et al, Nova Southeastern University, University of Alberta  ::  www.benthamscience.com/journal/ Summary and review of the above paper INTRODUCTION:  Recent research into the binding of anaesthetic molecules looks to revive the idea of hydrophobic pockets in the microtubules of neurons as the most suitable binding site for anaesthetic molecules. This could Read more […]

Recurrent neural processing

Posted by

Towards a neural stance on consciousness :: Victor Lamme, University of Amsterdam :: Trends in Cognitive Science, Vol. 10, No. 11, 25 September 2006 :: www.cell.com/trends/cognitive-sciences/home Summary and review of the above article Lamme says that he wishes to approach the question of consciousness from the direction of neuroscience. He asks why it is that some neural processes produce conscious experience, but others do not. Certain distinctions between conscious and unconscious processing Read more […]

Noise and unreliability of synapses

Posted by

Detecting and estimating signals over noisy and unreliable synapses  ::  Amit Manwani & Christof Koch, California Institute of Technology  ::  Neural Computation 13, pp. 1-33, (2000) http://www.mitpressjournals.org/loi/neco Summary and review of the above paper This paper discusses the relationship between noise and information transfer in the brain. Synaptic transmission is known to be unreliable and probabilistic. Single cortical synapses cannot transfer information reliably. Therefore, Read more […]

Ex Machina and consciousness

Posted by

The recent science fiction film, Ex Machina, about the invention of a conscious android takes us straight to the heart of the nature of consciousness. The android, named Ava, has a clear choice, preference and desire to be free from the underground chamber in which she is confined, and also to be free from the direction of her inventor. The inventor, Nathan, asks the other main character, Caleb, to go beyond the Turing test. This is good advice as the Turing test was an annoying distraction Read more […]

Explanatory gap

Posted by

The Computational Explanatory Gap James Reggia, Derek Monner & Jared Sylvester :: Journal of Consciousness Studies, 21, No. 9&10, 2014, pp. 153-78 :: www.imprint.co.uk/jcs.html Summary and review of the above paper INTRODUCTION: The durability of the explanatory gap between neural processing and consciousness is seen as surprising given the successes of neuroscience in recent decades. Models of cognitive processing still require external direction, which is exactly what the conscious Read more […]

Pain and consciousness

Posted by

Pain and the PAG (periaqueductal grey matter): learning from painful mistakes Falk Eippert & Irene Tracey, University of Oxford, based on Roy et al, Nature Neuroscience, Vol. 17, No. 11, November 2014 :: http://www.nature.com/neuro/index.html Summary and review of the above paper INTRODUCTION: In this paper, the orbitofrontal and the anterior cingulate brain regions are seen to be at the heart of attaching value to inputs. The study contrasts the influence of rewarding stimuli on the Read more […]

Integrated information theory

Posted by

Integrated information theory http://en.wikipedia.org/wiki/Integrated_information_theory Summary and review of the above paper INTRODUCTION: Tononi has produced half a theory of consciousness. He identifies how recent neuroscience has shown that consciousness is related to parts of the brain on which information convergences. He also grasps that consciousness has to be a fundamental aspect of reality. However, he seems to cling to the idea that it can somehow arise from individual bits of Read more […]

Emotional and Cognitive Processing

Posted by

The field of affective neuroscience, initiated by Panksepp and Ledoux, embraces the concept that emotional processes are based on brain structures that operate in parallel with cognitive processes, and can thus influence behaviour independently of cognition.